The Department of Physiology is a basic science department in the David Geffen School of Medicine at UCLA that was founded in 1952. Physiology is the study of how living systems function, through a comprehensive approach that builds upon fundamental principles of chemistry, physics, biology, and mathematics. The overarching goal is to understand the processes by which molecules, cells, and organs interact to maintain vitality and good health. The Department has a rich history of landmark discoveries in membrane transport, ion channel biophysics, membrane receptors, contractility, and the electrophysiology of nerve, muscle and heart. In recent years, our faculty have expanded upon this foundation to develop a diverse portfolio of research programs.